Zopiclone has agonist effects (i.e., enhancers) on benzodiazepine BZ1 receptors, associated with the release of GABA or gamma-aminobutyric acid . GABA, which reduces the excitability of neurons, is the main inhibitory neurotransmitter of the central nervous system; It also promotes muscle relaxation. This mechanism of action is equivalent to that of benzodiazepines, which have been the most widely used anxiolytics for many decades. Both types of drug bind to the same classes of gabaergic receptor, producing very similar therapeutic effect... read full review »