This product almost killed my Great Pyrenees. Within an hour he went from normal to salivating, panting, muscle spasms, crying, biting at his hind end and tail, not walking... Took him to vet had anal glands expressed along with other tests and found nothing. Then I realized it was this product and imediately started bathing him. Found that many people have suffered the same reaction after looking up this product. I cannot believe it is still sold! read full review »