At the time I received my 4-month supply back in June, the bottle had no directions or indications on it (i.e., take w/meals, take in the morning, etc.). I took 2 in the evening and woke up at 1:30 a.m. with severe heart palpitations and shortness of breath. I called 911 and spent 3 hours in the ER (e.k.g., blood analysis, I.V.) due to Resveratrol Ultra...my heart rate and blood pressure were through the roof (I have never had palpitations nor high bp prior). Needlesstosay, I called to obtain an RMA number which I received from Kim. I returned... read full review »