I applied Sentry Pro XFO to my 88 lb. Border Collie (61 lb- >) last night around 11 p.m. He was up the entire night pacing, and running up and down the stairs. When he would lay down, it would be for maybe a ten minute period in which he would excessively lick or bite at himself or lick is blankets until they were soaked. He also was panting more than usual. Then, around 4:00 a.m. he began coughing and hacking. I realized this had to be a reaction to the flea treatment. I gave him 50 mg. of Benedryl and washed him off with Dawn dish washing... read full review »