What is peritoneal cancer? Cancer that has spread to the lining surfaces of the peritoneal (abdominal) cavity from ovarian cancer, primary colorectal cancer, appendiceal cancer, or mesothelioma and pseudomyxoma peritonei—known as peritoneal carcinomatosis—are cancers that are frequently referred to as peritoneal cancers.
Whether peritoneal cancer starts in the peritoneum or spreads from somewhere else (colon, appendix, ovary), it is considered advanced (stage IV) once it’s in the peritoneum and might be referred to as peritoneal carcinomatosis.
Who is at risk for peritoneal cancer?
It's not known exactly what causes peritoneal cancer, though the process begins when a series of mutations in peritoneal cells results in out-of-control growth. This could be related to a prior cancer that has now spread to the peritoneum or another cancer type known as a primary peritoneal cancer.
Is peritoneal cancer genetic?
Peritoneal cancer is not a directly hereditary cancer but the risk of its development in individuals is increased if they have mutations in their genetic makeup (BRAC1, BRAC2 genes, for example). Other risk factors are sex (females are at higher risk); older age is also a risk factor.
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